Modafinil works by affecting the brain's dopamine and noradrenaline systems, which play a key role in regulating the sleep-wake cycle. It blocks dopamine reuptake, increasing dopamine availability in the brain and improving attention and cognitive function. In addition, modafinil affects other wake-promoting neurotransmitters such as histamine and orexin, supporting the brain's ability to stay awake and alert throughout the day.
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